Detalhe da pesquisa
1.
CFTR is required for zinc-mediated antibacterial defense in human macrophages.
Proc Natl Acad Sci U S A
; 121(8): e2315190121, 2024 Feb 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38363865
2.
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.
Proc Natl Acad Sci U S A
; 120(4): e2212813120, 2023 01 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36649417
3.
TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.
Eur J Immunol
; 53(7): e2250056, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37058370
4.
The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs.
J Biol Chem
; 298(5): 101857, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35337798
5.
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1ß production in murine macrophages via distinct mechanisms.
J Leukoc Biol
; 111(2): 327-336, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34811804
6.
SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages.
Cell Rep
; 36(10): 109662, 2021 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34496234
7.
Frontline Science: LPS-inducible SLC30A1 drives human macrophage-mediated zinc toxicity against intracellular Escherichia coli.
J Leukoc Biol
; 109(2): 287-297, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32441444
8.
SCIMP is a universal Toll-like receptor adaptor in macrophages.
J Leukoc Biol
; 107(2): 251-262, 2020 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31468585
9.
Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense.
Science
; 370(6514)2020 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33060333
10.
Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.
Cell Rep
; 30(8): 2712-2728.e8, 2020 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32101747
11.
pTRAPs: Transmembrane adaptors in innate immune signaling.
J Leukoc Biol
; 2018 Mar 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29601097